Rifamycin O

Anti-tuberculosis drug-synthesis intermediate and research tool for antibiotic development

Product Overview & Features

Anti-tuberculosis drug-synthesis intermediate and research tool for antibiotic development

Rifamycin O is an oxidation intermediate derived from rifamycin B and is used to synthesize rifamycin derivatives. It also acts as a selective inhibitor of bacterial DNA-dependent RNA polymerase and is used to study antibiotic mechanisms and structure–activity relationships.

Chemical Formula: C₃₉H₄₇NO₁₄
Applicable Standard: Q/XJYLH 22-2026
CAS No.: 14487-05-9
Product Characteristics: Beige to dark orange powder
Packaging: 25kg/barrel

Drug Synthesis Intermediates

It is a key intermediate produced by the oxidation reaction of rifamycin B. It can be used to further synthesize other rifamycin derivatives and has important application value in the pharmaceutical industry.

Antibacterial Activity

It has certain antibacterial activity and can be used as a selective inhibitor of bacterial DNA-dependent RNA polymerase. It is effective against Mycobacterium (including Mycobacterium tuberculosis) and has good in vitro activity and in vivo efficacy against difficult-to-treat Mycobacterium abscessus infection.

Scientific Research Tools

It is used as a tool compound in the laboratory to study the mechanism of action of antibiotics and the structure-activity relationship of rifamycin compounds, which is helpful for the development of new antibacterial drugs.