Multi-target whitening, oil control and barrier repair all-round skin care active ingredient
Multi-target whitening, oil control and barrier repair all-round skin care active ingredient
Nicotinamide (niacinamide), is the amide form of vitamin B3. Its INCI name is NIACINAMIDE and its CAS number is 98-92-0. It has been included in the "Catalogue of Used Cosmetic Raw Materials (2021 Edition)" and is used for skin protectants, moisturizers, and whitening agents. Its core functions are whitening and brightening, oil control and acne removal, barrier repair and antioxidant and anti-aging. It has multiple targets to improve uneven skin tone, dullness, oiliness, sensitive redness and loose fine lines. It has good water solubility and a stable pH range of 5.0-7.0. It can be compounded with sodium hyaluronate, ectoine, etc., and is suitable for dosage forms such as essence, cream, and lotion.
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Inhibits the transport of melanosomes from melanocytes to keratinocytes, downregulates tyrosinase activity, accelerates the shedding of old dead skin cells containing melanin, blocks the melanin transmission chain in multiple dimensions, and improves uneven skin tone and dullness.
Regulates the sebaceous gland cell signaling pathway, reduces the synthesis and secretion of fatty acids and triglycerides in sebum, while inhibiting the reproduction of Propionibacterium acnes, reducing oil production from the source, and improving enlarged pores.
Promote the synthesis of ceramide and cholesterol in the stratum corneum, activate serine palmitoyl transferase activity, enhance adhesion between horny cells, reduce transepidermal water loss, and help sensitive muscles return to stability.
Activate antioxidant systems such as glutathione and superoxide dismutase in the skin, eliminate oxidative damage to collagen and elastic fibers caused by free radicals, and delay fine lines and skin sagging.
